eALM1192 | mTOR inhibitor | Probechem Biochemicals

Chemical Structure : eALM1192

eALM1192 (eALM-1192)

Catalog No.: PC-28445Not For Human Use, Lab Use Only.

eALM1192 is a highly potent and selective mTOR inhibitor with IC50 of 2.3 nM, 37-fold selectivity over DNA-PK and excellent kinome selectivity, exhibits sub-nanomolar (IC50=5.6 nM) antiproliferative activity for SW48 cells.

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Biological Activity

Physicochemical Properties

M.Wt	445.48
Formula	C23H23N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	prop-2-yn-1-yl 4-((4-amino-5-(2-aminobenzo[d]oxazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)piperidine-1-carboxylate

References

1. Lorente-Macías Á, et al. RSC Med Chem. 2026 Aug 13. doi: 10.1039/d6md00572a.

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eALM1192 (eALM-1192)

Biological Activity

Physicochemical Properties

References

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