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iNOS inhibitor 12

Chemical Structure : iNOS inhibitor 12

CAS No.: 268730-08-1

iNOS inhibitor 12

Catalog No.: PC-62229Not For Human Use, Lab Use Only.

iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.

    Physicochemical Properties

    M.Wt 336.395
    Formula C19H20N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(4-((4-methoxypyridin-2-yl)amino)piperidine-1-carbonyl)benzonitrile

    References

    1. Garcin ED, et al. Nat Chem Biol. 2008 Nov;4(11):700-7.

    2. Connolly S, et al. J Med Chem. 2004 Jun 3; 47(12):3320-3.

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