Chemical Structure : kb NB 142-70
CAS No.: 1233533-04-4
Catalog No.: PC-63036Not For Human Use, Lab Use Only.
kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM, 58.7 nM and 53.2 nM for PKD1, PKD2, and PKD3, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $348 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM, 58.7 nM and 53.2 nM for PKD1, PKD2, and PKD3, respectively.
kb NB142 70 displays 10-fold increase in the in vitro PKD1 inhibitory potency versus CID755673.
kb NB142 70 inhibits PC-3, PANC-1, CFPAC-1 cellular growth with IC50 of 5-30 uM.
| M.Wt | 251.318 | |
| Formula | C11H9NO2S2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one |
|
1. Bravo-Altamirano K, et al. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.
2. Guo J, et al. Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright