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Chemical Structure : mutant IDH1 inhibitor VVS
Catalog No.: PC-35208Not For Human Use, Lab Use Only.
mutant IDH1 inhibitor VVS is a potent, selective c with nanomolar potency against both IDH1 R132H and IDH1 R132C, efficiently suppresses the cell-based production of D-2-HG in an HEK293 mutant embryonic kidney cell line.
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mutant IDH1 inhibitor VVS is a potent, selective mutant IDH1 inhibitor with nanomolar potency against both IDH1 R132H and IDH1 R132C, efficiently suppresses the cell-based production of D-2-HG in an HEK293 mutant embryonic kidney cell line.
| M.Wt | 366.509 | |
| Formula | C22H30N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Deng G, et al. J Biol Chem. 2015 Jan 9;290(2):762-74.
2. Ma T, et al. J Med Chem. 2018 Jun 18. doi: 10.1021/acs.jmedchem.8b00159.
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