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nor-NOHA acetate

Chemical Structure : nor-NOHA acetate

CAS No.: 1140844-63-8

nor-NOHA acetate (N-Omega-hydroxy-l-norarginine diacetate salt)

Catalog No.: PC-38062Not For Human Use, Lab Use Only.

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 uM, 20-fold lower than the Ki of 10 uM observed for NOHA.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 uM, 20-fold lower than the Ki of 10 uM observed for NOHA.
Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC50 of 10-12 µM.

Physicochemical Properties

M.Wt 296.28
Formula C9H20N4O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S,E)-2-amino-4-((amino(hydroxyamino)methylene)amino)butanoic acid compound with acetic acid (1:2)

References

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