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Chemical Structure : p32 inhibitor M36
CAS No.: 802555-85-7
Catalog No.: PC-62549Not For Human Use, Lab Use Only.
p32 inhibitor M36 is a novel small molecule inhibitor of p32 mitochondrial protein, binds directly to p32 and inhibits p32 association with LyP-1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $238 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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p32 inhibitor M36 is a novel small molecule inhibitor of p32 mitochondrial protein, binds directly to p32 and inhibits p32 association with LyP-1.
p32 inhibitor M36 inhibits glioma cell proliferation with IC50 of 7.3 uM under low glucose (2 mM) conditions.
p32 inhibitor M36 also is a potent inhibitor of patient-derived neurospheres with IC50 of 2.8 uM.
p32 inhibitor M36 selectively targets high p32 expressing cells, promotes an increase in lactate production resulting in media acidification.
| M.Wt | 448.531 | |
| Formula | C23H28N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,1'-(propane-1,3-diyl)bis(3-(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea) |
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1. Yenugonda V, et al. J Transl Med. 2017 Oct 18;15(1):210.
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