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Chemical Structure : pan-IFN inhibitor 5k
Catalog No.: PC-38756Not For Human Use, Lab Use Only.
pan-IFN inhibitor 5k is a potent and selective inhibitor of interferon-induced JAK-STAT signalling, blocks IFNγ activation of JAK-STAT signalling, also inhibits type I and III IFN-induced STAT phosphorylation in vitro.
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pan-IFN inhibitor 5k is a potent and selective inhibitor of interferon-induced JAK-STAT signalling, blocks IFNγ activation of JAK-STAT signalling, also inhibits type I and III IFN-induced STAT phosphorylation in vitro.
pan-IFN inhibitor 5k selectively inhibits IFN-induced tyrosine phosphorylation of STAT1 and STAT2, with no significant effect on STAT1 activation by EGF.
pan-IFN inhibitor 5k reduces bleeding in model of haemorrhagic colitis in vivo.
| M.Wt | 434.417 | |
| Formula | C23H12F2N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Thoidingjam LK, et al. Angew Chem Int Ed Engl. 2022 May 25.
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