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Cat. No. Product Name Information
PC-70167

OSSK-674842

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.
PC-45712

BPO-27 racemate

BPO-27 is a potent, metabolically stable CFTR inhibitor (IC50= 8 nM).
PC-45770

KM11060

A potent corrector of the F508del-CFTR trafficking defect that partially restores F508del trafficking and increases maturation significantly in BHK cells (10 nM for 24 h or 10 uM for 2 h).
PC-45455

GlyH-101

A potent CFTR inhibitor with Ki of 4.3 uM.
PC-45456

IOWH-032

A novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays for the treatment of cystic fibrosis.
PC-45711

(R)-BPO-27

(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance with IC50 of 4 nM.

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