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Cat. No. Product Name CAS No. Information
PC-45247

Valacyclovir

124832-26-4

Valacyclovir is an antiviral agent that acts as a very potent inhibitor of viral DNA polymerase; a prodrug of aciclovir for management of herpes simplex (HSV), herpes zoster and herpes B infection.

HSV Infection

Approved

PC-63468

FV-100

956483-03-7 FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.

HSV Infection

Phase 3 Clinical

PC-60382

Amenamevir

841301-32-4 A potent viral helicase-primase inhibitor that possesses antiviral activity against VZV, HSV1 and HSV2 with EC50 of 0.028-0.1 uM; exerts equipotent activity against VZV, HSV-1 and HSV-2 through prevention of viral DNA replication; also shows activity against aciclovir-resistant VZV.

HSV Infection

Appoved

PC-45243

Acyclovir

59277-89-3 An antiviral agent that competitively inhibits and inactivates HSV-specified DNA polymerases preventing further viral DNA synthesis without affecting the normal cellular processes; primarily used for the treatment of HSV infections.

HSV Infection

Approved

PC-45248

Valacyclovir hydrochloride

124832-27-5 An antiviral agent that acts as a very potent inhibitor of viral DNA polymerase; a prodrug of aciclovir for management of herpes simplex (HSV), herpes zoster and herpes B infection.

HSV Infection

Approved

PC-45855

Fiacitabine

69123-90-6 A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively, shows minimal cytotoxicity; more potent than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine.

HSV Infection

Phase 2 Discontinued

PC-45957

SPK-601

1096687-52-3 A potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor; shows antiviral activity against herpes simplex virus (HSV); a novel antimicrobial agent.

HSV Infection

Phase 1 Clinical

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