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Cat. No. Product Name Information
PC-35916

SKLB-C05

TOPK inhibitor

SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis.
PC-43047

OTS-964

TOPK inhibitor

OTS-964 is a dimethylated derivative of OTS514 and potent, selective TOPK inhibitor with IC50 of 28 nM, exhibits excellent in vivo efficacy with liposomal formulation.
PC-70142

ADA-07

TOPK inhibitor

ADA-07 is a novel potent TOPK inhibitor that effectively suppresses SUV-induced activation of MAPKs signal transduction resulting in reduced SUV-induced skin carcinogenesis.
PC-42404

HI-TOPK-032

TOPK inhibitor

HI-TOPK-032 is a novel potent, specific TOPK inhibitor that has no effect on ERK1, JNK1, or p38 kinase activity.
PC-45487

OTS-514

TOPK inhibitor

OTS-514 (OTS514) is a highly potent and selective TOPK inhibitor with IC50 of 2.6 nM.

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