1Ai-4927

Chemical Structure : 1Ai-4927

CAS No.: 475108-18-0

Catalog No.: PC-24688Not For Human Use, Lab Use Only.

1Ai-4927 is a specific inhibitor of ribosomal protein Rps10 with IC50 of 6.1 uM, targets the eIF1A-RPS10 complex,1Ai-4927 binds only RPS10, but not affect eIF1A.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
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Biological Activity

1Ai-4927 is a specific inhibitor of ribosomal protein Rps10 with IC50 of 6.1 uM, targets the eIF1A-RPS10 complex,1Ai-4927 binds only RPS10, but not affect eIF1A.

Physicochemical Properties

M.Wt	454.87
Formula	C22H19ClN4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-3-(5-methylisoxazol-3-yl)urea

References

1. Hayat D, et al. EMBO J. 2025 May 12. doi: 10.1038/s44318-025-00449-6.

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1Ai-4927

Biological Activity

Physicochemical Properties

References

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