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2800Z

Chemical Structure : 2800Z

CAS No.: 1048966-16-0

2800Z

Catalog No.: PC-20270Not For Human Use, Lab Use Only.

2800Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

2800Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer.

Physicochemical Properties

M.Wt 547.61
Formula C30H33N3O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-(3-(3,4-dimethoxyphenethyl)-1-(3-methoxyphenyl)-2,5-dioxoimidazolidin-4-yl)-N-(4-ethoxyphenyl)acetamide

References

1. Chen Zhang, et al. Front Cell Dev Biol. 2022 Jan 31;9:813233.

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