Chemical Structure : 3,4,3-LI(1,2-HOPO)
CAS No.:
110874-36-7
3,4,3-LI(1,2-HOPO)
(Enfipaxetan, HOPO 14-1)
Catalog No.: PC-27422Not For Human Use, Lab Use Only.
3,4,3-LI(1,2-HOPO) (Enfipaxetan) is a metal chelating agent, exhibits extremely high affinity for lanthanide metal ions, sensitizes the emission of Sm(III), Eu(III), and Tb(III) in the Visible range and the emission of Pr(III), Nd(III), Sm(III), and Yb(III).
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
3,4,3-LI(1,2-HOPO) (Enfipaxetan) is a metal chelating agent, exhibits extremely high affinity for lanthanide metal ions, sensitizes the emission of Sm(III), Eu(III), and Tb(III) in the Visible range and the emission of Pr(III), Nd(III), Sm(III), and Yb(III).
Physicochemical Properties
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M.Wt
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750.72
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Formula
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C34H38N8O12
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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N,N'-(butane-1,4-diyl)bis(1-hydroxy-N-(3-(1-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamido)propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide)
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References
1. Sturzbecher-Hoehne M, et al. 3,4,3-LI(1,2-HOPO): in vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation. Dalton Trans. 2011 Sep 7;40(33):8340-6.
2. Xu J, et al. J Med Chem. 1995 Jul 7;38(14):2606-14.
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