| Cat. No. |
Product Name |
Information |
| PC-27728 |
UCB-J
SV2A modulator
|
UCB-J is a selective allosteric modulator of synaptic vesicle protein 2A (SV2A) with pIC50 of 8.15 and 7.6 human and rat SV2A respectively. |
| PC-27727 |
ABBV-552
SV2A modulator
|
ABBV-552 (SDI-118) is a high-affinity, orally available positive synaptic vesicle glycoprotein 2 A (SV2A) modulator with IC50 of 13 nM in in vitro radioligand binding study using human recombinant SV2A (hSV2A). |
| PC-27712 |
XJ-4-85
PFKL activator
|
XJ-4-85 is a highly selective, covalent, allosteric phosphofructokinase-1 liver type (PFKL) activator with EC50 of 342.3 nM in substrate assays (4h), releases carnitine palmitoyltransferase 2 (CPT2) inhibitor destabilize cancer cell metabolism. |
| PC-27674 |
TS-002266
TUT4/7 inhibitor
|
TS-002266 is a potent and selective RNA terminal uridylyl transferase enzymes 4 and 7 (TUT4/7) inhibitor, blocks miRNA uridylation in vitro with biochemical IC50 of 69 and 16 nM for TUT4 and TUT7, respectively. |
| PC-27672 |
FUT8-IN-1
FUT8 inhibitor
|
FUT8-IN-1 is a potent, selective α-1,6-fucosyltransferase (FUT8) inhibitor with KD of 49 nM and IC50 50 uM. |
| PC-27617 |
ABT-E79
PGK1 inhibitor
|
ABT-E79 is a highly potent and selective PGK1 inhibitor, significantly inhibits TNBC cell proliferation. |
| PC-27604 |
OMDM-1
Anandamide uptake inhibitor
|
OMDM-1 is a potent, selective inhibitor of anandamide cellular uptake (ACU) with Ki of 2.4 uM, inhibits anandamide transport. |
| PC-27596 |
Isofagomine
Glycosidase inhibitor
|
Isofagomine (Afegostat) is a broad spectrum inhibitor of glycosidases, inhibits beta-glucosidase, glucoamylase, isomaltase, and alpha-glucosidase, specifically and reversibly binds lysosomal hydrolase acid β-glucosidase (GCase) in the ER with high affinity. |
| PC-27579 |
K303MP20
GPRC5B/C inhibitor
|
K303MP20 (MP20) is a small molecule inhibitor of orphan GPCR GPRC5B and GPRC5C dimerization, inhibits GPRC5B/C-mediated modulation of EP2, IP, and AT1 signaling in vitro and in vivo. |
| PC-27512 |
MAT2A inhibitor ZS34
MAT2A inhibitor
|
MAT2A inhibitor ZS34 is a potent, selective, and orally bioavailable MAT2A inhibitor with IC50 of 13.7 nM. |
| PC-27508 |
Tazbentetol
Synaptic regenerative agent
|
Tazbentetol (SPG302) is a pegylated benzothiazole derivative and synaptic regenerative small molecule, targets the cytoskeleton and induces the formation of new glutamatergic synapses. |
| PC-27505 |
JXL069
MPC inhibitor
|
Suvomipic (JXL069) is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 42.8 nM. |
