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Chemical Structure : 4-BBPB maleate
CAS No.: 207572-62-1
Catalog No.: PC-61601Not For Human Use, Lab Use Only.
4-BBPB maleate is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
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|---|---|---|---|
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4-BBPB maleate is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
4-BBPB maleate attenuates activity of neuronal nitric oxide synthase (nNOS), blunts ischemia-induced nitric oxide production, and provides neuroprotection in stroke models.
| M.Wt | 409.526 | |
| Formula | C25H31NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-phenyl-1-(4-phenylbutyl) piperidine maleate |
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1. Takahashi H, et al. Stroke. 1995 Sep;26(9):1676-82.
2. Narita N, et al. Eur J Pharmacol. 1995 Oct 6;293(3):277-80.
3. Yang ZJ, et al. Exp Neurol. 2010 Jan;221(1):166-74.
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