Chemical Structure : 4EGI-1
CAS No.:
315706-13-9
4EGI-1
(eIF4E/eIF4G inhibitor)
Catalog No. : PC-45737Not For Human Use, Lab Use Only.
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4573701
Biological Activity
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E).
Physicochemical Properties
M.Wt
451.2833
Formula
C18H12Cl2N4O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 35 mg/mL
Chemical Name/SMILES
Benzenepropanoic acid, α-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-
References
1. Moerke NJ, et al. Cell.
2. Wang W, et al. Oncotarget
3. Papadopoulos E, et al. Proc Natl Acad Sci U S A.
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