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Chemical Structure : 7DG
Catalog No.: PC-62200Not For Human Use, Lab Use Only.
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR.
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7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR; completely protectes macrophages from anthrax lethal toxin (LT)-induced pyroptotic cell death, a model for inflammasome-mediated caspase-1 activation, with an (IC50) of 5 uM.
| M.Wt | 422.51 | |
| Formula | C26H30O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hett EC, et al. Nat Chem Biol. 2013 Jun;9(6):398-405.
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