Chemical Structure : A-484954
CAS No.:
142557-61-7
A-484954
(A484954, A 484954)
Catalog No. : PC-70180Not For Human Use, Lab Use Only.
A-484954 (A484954) is a highly selective, small molecule eEF2K inhibitor with IC50 of 0.28 uM.
Packing Price Stock Quantity 5 mg $88 In stock 0 1 2 3 4 5 10 mg $148 In stock 0 1 2 3 4 5 25 mg $268 In stock 0 1 2 3 4 5 50 mg $428 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7018001
Biological Activity
A-484954 (A484954) is a highly selective, small molecule eukaryotic elongation factor 2 kinase (eEF2K) inhibitor with IC50 of 0.28 uM.
Physicochemical Properties
M.Wt
289.29
Formula
C13H15N5O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
References
1. Chen Z, et al. J Biol Chem.
2. Edupuganti R, et al. Bioorg Med Chem.
3. Kameshima S, et al. Am J Physiol Heart Circ Physiol.
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