Chemical Structure : A-770041
CAS No.:
869748-10-7
A-770041
(A770041, A 770041)
Catalog No. : PC-42786Not For Human Use, Lab Use Only.
A-770041 (A770041) is a potent and selective small-molecule inhibitor of Lck kinase with IC50 of 147 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4278601
Biological Activity
A-770041 (A770041) is a potent and selective small-molecule inhibitor of Lck kinase with IC50 of 147 nM.
Physicochemical Properties
M.Wt
621.7319
Formula
C34H39N9O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1H-Indole-2-carboxamide, N-[4-[1-[trans-4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-
References
1. Stachlewitz RF, et al. J Pharmacol Exp Ther
2. Burchat A, et al. Bioorg Med Chem Lett.
3. Duan Z, et al. BMC Cancer.
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