| Cat. No. |
Product Name |
Information |
| PC-73124 |
CH6953755
YES1 inhibitor
|
CH6953755 (CH 6953755) is a potent, selective, orally available YES1 kinase inhibitor with IC50 of 1.8 nM. |
| PC-72678 |
iHCK-37
Hck inhibitor
|
iHCK-37 (ASN05260065) is a potent and selective Hck inhibitor with Ki of 0.22 uM. |
| PC-72224 |
DGY-06-116
SRC inhibitor
|
DGY-06-116 (SRC inhibitor 15a) is a potent, selective, covalent Src inhibitor (biochemical IC50=3 nM) that taregrs a P-Loop cysteine (Cys277). |
| PC-35754 |
RK-20449
|
RK-20449 (RK20449) is a potent, small molecule inhibitor of hematopoietic cell kinase (HCK) with IC50 of 0.43 nM. |
| PC-35102 |
TL02-59
Fgr kinase inhibitor
|
TL02-59 is a potent, selective, orally available inhibitor of Src-family kinase Fgr IC50 of 0.03 nM, also inhibits Lyn and Hck with IC50 of 0.1 and 160 nM, respectively. |
| PC-63531 |
KX2-361
Src/tubulin inhibitor
|
KX2-361 (KX 02) is a potent, orally active dual Src signaling/tubulin polymerization inhibitor, KX2-361 is a non-ATP competitive Src inhibitor, demonstrates broad anti-tumor activity both in vitro and in vivo. |
| PC-62865 |
KB SRC 4
|
KB SRC 4 (c-Src-IN-4) is a potent, highly selective c-Src kinase inhibitor with Ki of 44 nM, does not inhibit c-Abl up to 125 uM, and binds to c-Src-TM (Q275G, C277Q, F278Y) with similar potency to that of wild-type c-Src. |
| PC-61227 |
NMT1 inhibitor B13
|
NMT1 inhibitor B13 (LCL4) is a myristoylCoA analog that acts as a small molecule inhibitor of NMT1 with IC50 of 77.6 uM, blocks Src myristoylation and Src localization to the cytoplasmic membrane. |
| PC-61226 |
LCL204
NMT1 inhibitor
|
LCL204 is a small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4. |
| PC-61141 |
eCF506
Src inhibitor
|
eCF506 is a highly potent, selective, orally available Src family kinase inhibitor with IC50 of <0.5 nM, <0.5 nM and for Src, Yes and Fyn kinases respectively, >950-fold selectivity for Src over ABL. |
| PC-60888 |
PD166285
Src/Wee1/Myt1 inhibitor
|
PD166285 (PD 0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM, also inhibits the checkpoint kinases Wee1 and Myt1. |
| PC-60584 |
JP-153
|
JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs. |
