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A2ti-2

Chemical Structure : A2ti-2

CAS No.: 482646-13-9

A2ti-2 (S100A10-ANXA2 inhibitor)

Catalog No.: PC-27212Not For Human Use, Lab Use Only.

A2ti-2 (S100A10-ANXA2 heterotetramer inhibitor-2) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 230 nM (Annexin A2/S100A10 heterotetramer (A2t)), blocks HPV16 infection and entry into HeLa cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A2ti-2 (S100A10-ANXA2 heterotetramer inhibitor-2) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 230 nM (Annexin A2/S100A10 heterotetramer (A2t)), blocks HPV16 infection and entry into HeLa cells.

Physicochemical Properties

M.Wt 354.43
Formula C18H18N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((4-Phenyl-5-((o-tolyloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

References

1. Tummala R K Reddy, et al. ChemMedChem. 2012 Aug;7(8):1435-46.

2. Andrew W Woodham, et al. J Antimicrob Chemother. 2015;70(6):1686-90.

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