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Chemical Structure : AA 41612
CAS No.: 433690-62-1
Catalog No.: PC-62204Not For Human Use, Lab Use Only.
AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $148 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | $458 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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AA41612 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 15.8 nM.
AA41612 attenuated melanopsin photocurrent in a dose-dependent manner, inhibited melanopsin photoresponses without inhibiting rod/cone function.
AA41612 reversibly attenuateed melanopsin-mediated photoresponses.
| M.Wt | 324.216 | |
| Formula | C12H15Cl2NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-[(2,5-Dichloro-4-methoxyphenyl)sulfonyl]piperidine |
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1. Jones KA, et al. Nat Chem Biol. 2013 Oct;9(10):630-5.
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