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Chemical Structure : ACC2 inhibitor 2e
Catalog No.: PC-73298Not For Human Use, Lab Use Only.
ACC2 inhibitor 2e is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 1.9 nM and 1950 nM for ACC2 and ACC1, respectively.
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ACC2 inhibitor 2e is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 1.9 nM and 1950 nM for ACC2 and ACC1, respectively.
ACC2 inhibitor 2e exhibited good PK profile and in vivo antidiabetic efficacy in C57BL/6 mice.
| M.Wt | 417.908 | |
| Formula | C20H20ClN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nishiura Y, et al. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2498-2503.
2. Takagi H, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):256-263.
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