| Cat. No. |
Product Name |
Information |
| PC-20376 |
ND-646
Acetyl-CoA carboxylase inhibitor
|
ND-646 (ND646) is a potent, selective and allosteric inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of 3.5 and 4.2 nM for hACC1 and hACC2, respectively. |
| PC-73297 |
A-908292
ACC2 inhibitor
|
A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM). |
| PC-72818 |
IMA-1
ALOX12 inhibitor
|
IMA-1 (ALOX12-ACC1 inhibitor IMA-1) is a small molecule that interrupt the arachidonate 12-lipoxygenase (ALOX12)-acetyl-CoA carboxylase 1 (ACC1) interaction. |
| PC-72388 |
PF-05221304
ACC inhibitor
|
PF-05221304 (PF 05221304) is a novel potent, selective, liver-targeted dual acetyl-CoA carboxylase (ACC1/2) inhibitor with IC50 of 13/9 nM (hACC1/2). |
| PC-36170 |
ND-654
Acetyl-CoA carboxylase inhibitor
|
ND-654 (ND654) is a novel potent, liver-specific acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 3/8 nM for human ACC1/ACC2, respectively. |
| PC-63466 |
PF-05175157
|
PF-05175157 (PF-5175157) is a potennt Acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 27 and 33 nM for hAAC1 and hACC2, respectively. |
| PC-61377 |
Firsocostat
Acetyl-CoA carboxylase inhibitor
|
Firsocostat (ND-630, NDI-010976, GS-0976) is a highly potent, selective inhibitor of acetyl-CoA carboxylase (ACC) with IC50 of 2.1 and 6.1 nM for isozymes ACC1 and ACC2, respectively. |
| PC-61204 |
MK-4074
Acetyl-CoA carboxylase inhibitor
|
MK-4074 is a potent, liver-specific, orally active inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of ~3 nM. |
| PC-42306 |
TOFA
Acetyl-CoA carboxylase inhibitor
|
TOFA (RMI14514, MDL14514) is an indirect, allosteric inhibitor of Acetyl-CoA carboxylase-α (ACCA) and fatty acid synthesis. |
| PC-73298 |
ACC2 inhibitor 2e
ACC2 inhibitor
|
ACC2 inhibitor 2e is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 1.9 nM and 1950 nM for ACC2 and ACC1, respectively. |
| PC-72105 |
ACC1 inhibitor Compound 1
ACC1 inhibitor
|
ACC1 inhibitor Compound 1 is a potent, highly selective, oral ACC1 inhibitor with IC50 of 0.58 nM (hACC1), no effect on hACC2 (IC50>10 uM). |
| PC-61206 |
MK-4074 sodium salt
|
MK-4074 is a potent, liver-specific, orally active inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of ~3 nM. |
