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Chemical Structure : ACOU085
Catalog No.: PC-49796Not For Human Use, Lab Use Only.
ACOU085 (ACOU 085) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with higher potency than ML-213 in the nanomolar range.
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ACOU085 (ACOU 085) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with higher potency than ML-213 in the nanomolar range.
ACOU085 reduces age-related outer hair cells (OHCs) loss in the senescence-accelerated mouse prone 8 (SAMP8) mice model, has potential effect against ge-related hearing loss (ARHL) and other hearing impairments related to compromised KV7.4 function.
| M.Wt | 342.79 | |
| Formula | C15H13ClF2N2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Peixoto Pinheiro B, et al. Cell Death Dis. 2022 Jul 11;13(7):595.
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