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Chemical Structure : AF38469
CAS No.: 1531634-31-7
Catalog No.: PC-43219Not For Human Use, Lab Use Only.
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 100 mg | $798 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
AF38469 shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin ETA/B, MMP-12).
| M.Wt | 324.2546 | |
| Formula | C15H11F3N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 43 mg/mL |
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| Chemical Name/SMILES |
Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)- |
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1. Schrøder TJ, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.
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