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AGH-107

Chemical Structure : AGH-107

CAS No.: 2172907-10-5

AGH-107 (AGH107)

Catalog No.: PC-73303Not For Human Use, Lab Use Only.

AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.
AGH-107 exhibited high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.

Physicochemical Properties

M.Wt 337.164
Formula C13H12IN3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Hogendorf AS, et al. Sci Rep. 2017 May 4;7(1):1444.

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