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Chemical Structure : ARN726
CAS No.: 1628343-77-0
Catalog No.: PC-62874Not For Human Use, Lab Use Only.
ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA).
ARN726 shows no interaction with a panel of 28 biologically relevant targets comprising lipid-metabolizing and inflammation-related enzymes.
ARN726 exerts profound anti-inflammatory effects in both mouse models and human macrophages.
| M.Wt | 268.357 | |
| Formula | C14H24N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate |
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1. Ribeiro A, et al. ACS Chem Biol. 2015 Aug 21;10(8):1838-46.
2. Bonezzi FT, et al. J Pharmacol Exp Ther. 2016 Mar;356(3):656-63.
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