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Chemical Structure : ART812
Catalog No.: PC-49362Not For Human Use, Lab Use Only.
ART812 (ART-812) is a selective small molecule DNA polymerase theta (Polθ) in vivo probe, recapitulates the phenotype of Polθ loss and is efficacious in a model of PARP inhibitor resistant TNBC in vivo.
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ART812 (ART-812) is a selective small molecule DNA polymerase theta (Polθ) in vivo probe, recapitulates the phenotype of Polθ loss and is efficacious in a model of PARP inhibitor resistant TNBC in vivo.
| M.Wt | 461.798 | |
| Formula | C19H16ClF4N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Martin L Stockley, et al. J Med Chem. 2022 Oct 6. doi: 10.1021/acs.jmedchem.2c01142.
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