Catalog No.: PC-28104Not For Human Use, Lab Use Only.
AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis.
AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis.
Physicochemical Properties
M.Wt
126.12
Formula
C5H6N2O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
5-methylpyrazole-3-carboxylic acid
References
1. Sugden MC, et al. Biochem J. 1982 Jun 15;204(3):749-56.
2. Adage T, et al. Eur Neuropsychopharmacol. 2008;18(3):200-214.
3. Gong N, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):282-93.
4. Sugden MC, et al. Metabolism. 1999 Jun;48(6):707-15.
