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Chemical Structure : AS1134900
Catalog No.: PC-49092Not For Human Use, Lab Use Only.
AS1134900 is a potent, highly selective, allosteric inhibitor of NADP+-dependent malic enzyme 1 (ME1), uncompetitively inhibits ME1 activity in the presence of its substrates NADP+ and malate, binds outside the ME1 active site in a novel allosteric site.
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AS1134900 is a potent, highly selective, allosteric inhibitor of NADP+-dependent malic enzyme 1 (ME1), uncompetitively inhibits ME1 activity in the presence of its substrates NADP+ and malate, binds outside the ME1 active site in a novel allosteric site.
| M.Wt | 466.567 | |
| Formula | C25H22N8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tomohiro Yoshida, et al. Biochemistry. 2022 Jul 12. doi: 10.1021/acs.biochem.2c00123.
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