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Chemical Structure : AS601245
CAS No.: 345987-15-7
Catalog No.: PC-42785Not For Human Use, Lab Use Only.
AS601245 is a potent and selective inhibitor of JNK with IC50s of 70/220/150 nM for JNK1/2/3 respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $548 | In stock | |
| 100 mg | Get quote |
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AS601245 is a potent and selective inhibitor of JNK with IC50s of 70/220/150 nM for JNK1/2/3 respectively.
AS601245 is less potent for c-Src, c-Raf, p38a kinases.
AS601245 exhibits in vitro and in vivo anti-inflammatory potential.
| M.Wt | 372.4462 | |
| Formula | C20H16N6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 35 mg/mL |
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| Chemical Name/SMILES |
2-Benzothiazoleacetonitrile, -[2-[[2-(3-pyridinyl)ethyl]amino]-4-pyrimidinyl]- |
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1. Gaillard P, et al. J Med Chem. 2005 Jul 14;48(14):4596-607.
2. Carboni S, et al. J Pharmacol Exp Ther. 2004 Jul;310(1):25-32.
3. Carboni S, et al. Br J Pharmacol. 2008 Jan;153(1):157-63.
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