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Chemical Structure : ASP7967
Catalog No.: PC-20404Not For Human Use, Lab Use Only.
ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM.
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ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM.
Oral administration of 100 mg/kg ASP7967 upregulated the serum hEPO concentration by ∼7.2-fold over the vehicle control in mice.
| M.Wt | 406.40 | |
| Formula | C20H16F2N8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Keisuke Fukunaga, et al. J Am Chem Soc. 2023 Mar 29. doi: 10.1021/jacs.2c12332.
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