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Chemical Structure : AUDA-BE
Catalog No.: PC-70251Not For Human Use, Lab Use Only.
The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively.
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The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.
| M.Wt | 448.692 | |
| Formula | C27H48N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608.
2. Schmelzer KR, et al. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7.
3. Motoki A, et al. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2128-34.
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