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Chemical Structure : AVN-211
Catalog No.: PC-61511Not For Human Use, Lab Use Only.
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
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AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
AVN-211 shows a similar or better anxiolytic efficacy than fenobam, rufinamide, lorazepam, and buspirone in an elevated plus-maze model.
AVN-211 significantly delayes or partially halts the progressive decline in memory function associated with AD.
| M.Wt | 333.424 | |
| Formula | C15H15N3O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ivachtchenko AV, et al. Mol Pharm. 2016 Mar 7;13(3):945-63.
2. Morozova MA,et al. CNS Spectr. 2014 Aug;19(4):316-23.
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