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Chemical Structure : AZD-7762
CAS No.: 860352-01-8
Catalog No.: PC-42769Not For Human Use, Lab Use Only.
AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
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AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.
AZD-7762 shows less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
AZD-7762 enhances the radiosensitivity of mutated p53 tumor cell lines and HT29 xenografts.
| M.Wt | 362.4218 | |
| Formula | C17H19FN4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Thiophenecarboxamide, 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl- |
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1. Zabludoff SD, et al. Mol Cancer Ther. 2008 Sep;7(9):2955-66.
2. Mitchell JB, et al. Clin Cancer Res. 2010 Apr 1;16(7):2076-84.
3. Morgan MA, et al. Cancer Res. 2010 Jun 15;70(12):4972-81.
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