Catalog No.: PC-28726Not For Human Use, Lab Use Only.
AZD9750 is a potent, selective and orally bioavailable Androgen Receptor (AR) PROTAC degrader with DC50 of 10 nM and 12 nM for AR WT and AR L702H respectively. showed extensive degradation of AR, including L702H AR (Dmax >100%).
AZD9750 is a potent, selective and orally bioavailable Androgen Receptor (AR) PROTAC degrader with DC50 of 10 nM and 12 nM for AR WT and AR L702H respectively. showed extensive degradation of AR, including L702H AR (Dmax >100%).
AZD9750 inhibits tumor growth in vivo in a mouse prostate cancer xenograft model.
