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Chemical Structure : Actinomycin D
CAS No.: 50-76-0
Catalog No.: PC-45350Not For Human Use, Lab Use Only.
A chemotherapy agent that has the ability to inhibit transcription.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $72 | In stock | |
| 50 mg | $316 | In stock | |
| 250 mg | Get quote |
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A chemotherapy agent that has the ability to inhibit transcription; binds to DNA at the transcription initiation complex and preventing elongation of RNA chain by RNA polymerase; can also interfere with DNA replication; leads to the accumulation of transcriptionally active p53 in the nucleus of HeLa, CaSki, and SiHa cells.
| M.Wt | 1255.417 | |
| Formula | C62H86N12O16 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 27 mg/mL; DMSO: 250 mg/mL (Need ultrasonic); Methanol: 6.2 mg/mL; Methanol: 20 mg/mL (Need ultrasonic); H2O: < 12.5 mg/mL |
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| Chemical Name/SMILES |
Actinomycin D |
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1. Hietanen S, et al. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8501-6.
2. Sobell HM. Proc Natl Acad Sci U S A. 1985 Aug;82(16):5328-31.
3. Uberti EM, et al. Gynecol Oncol. 2009 Dec;115(3):476-81.
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