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Adhesamine

Chemical Structure : Adhesamine

CAS No.: 462605-73-8

Adhesamine

Catalog No.: PC-62425Not For Human Use, Lab Use Only.

Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth; induces apparently normal cell adhesion accompanied by organized actin structures and activation of focal adhesion kinase and ERK1/2 mitogen-activated protein kinases; a cell-attaching reagent for cell engineering and basic cell biology.

Physicochemical Properties

M.Wt 670.494
Formula C24H32Cl4N8O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,12-bis(6-chloro-5-formyl-2-(methylthio)pyrimidin-4-yl)-3,6,9,12-tetraazadispiro[5.2.59.26]hexadecane-6,9-diium chloride

References

1. Yamazoe S, et al. Chem Biol. 2009 Jul 31;16(7):773-82.

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