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Alexidine dihydrochloride

Chemical Structure : Alexidine dihydrochloride

CAS No.: 1715-30-6

Alexidine dihydrochloride

Catalog No.: PC-25950Not For Human Use, Lab Use Only.

Alexidine dihydrochloride is an anticancer agent that targets mitochondrial tyrosine phosphatase PTPMT1, induces mitochondrial apoptosis, also is a TAZ-TEAD binding inhibitor capable of suppressing TAZ-induced migration and invasion in breast cancer cells.

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Biological Activity

Alexidine dihydrochloride is an anticancer agent that targets mitochondrial tyrosine phosphatase PTPMT1, induces mitochondrial apoptosis, also is a TAZ-TEAD binding inhibitor capable of suppressing TAZ-induced migration and invasion in breast cancer cells.
Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens.

Physicochemical Properties

M.Wt 581.72
Formula C26H58Cl2N10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-Tetraazatetradecanediimidamide dihydrochloride

References

1. Ge A, et al. iScience. 2025 Nov 21;28(12):114116.

2. Mamouei Z, et al. mSphere. 2018 Oct 31;3(5). pii: e00539-18.

3. Doughty-Shenton D, et al. J Pharmacol Exp Ther. 2010 May;333(2):584-92.

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