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Amcasertib

Chemical Structure : Amcasertib

CAS No.: 1129403-56-0

Amcasertib (BBI-503)

Catalog No.: PC-45384Not For Human Use, Lab Use Only.

A small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.

Packing Price Stock Quantity
5 mg $280 In stock
10 mg $400 In stock
50 mg $1200 In stock
100 mg $1680 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases; targets and inhibits one or more pathways involved in cancer stem cell survival, shows potential antineoplastic activity.

Liver Cancer

Phase 2 Clinical

Physicochemical Properties

M.Wt 539.691
Formula C31H33N5O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-

References

1. Marcucci F, et al. Front Oncol. 2016 May 10;6:115.

2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.

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