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Anlotinib

Chemical Structure : Anlotinib

CAS No.: 1058156-90-3

Anlotinib (AL-3818, AL3818)

Catalog No.: PC-45681Not For Human Use, Lab Use Only.

Anlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Anlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.
Anlotinib (AL-3818) shows antitumor activity against tumor cells carrying mutations in PDGFR α, c-Kit, Met, and epidermal growth factor receptor (EGFR).

Physicochemical Properties

M.Wt 407.4375
Formula C23H22FN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 44 mg/mL

Chemical Name/SMILES

Cyclopropanamine, 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]-

References

1. Sun Y, et al. J Hematol Oncol. 2016 Oct 4;9(1):105.

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