Apamin | SK channel inhibitor | Probechem Biochemicals

Chemical Structure : Apamin

CAS No.: 24345-16-2

Apamin (Apamine)

Catalog No.: PC-26170Not For Human Use, Lab Use Only.

Apamin (Apamine) is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity.

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1 mg	$188	In stock
5 mg	$398	In stock
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Biological Activity

Apamin (Apamine) is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity.

Physicochemical Properties

M.Wt	2027.34
Formula	C79H131N31O24S4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2 (Disulfide bridge: Cys1-Cys11;Cys3-Cys15)

References

1. Cassell SJ, et al. Elife. 2025 Dec 4;14:RP107733.

2. Veress R, et al. Circ Res. 2025 Jul 18;137(3):386-399.

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Apamin (Apamine)

Biological Activity

Physicochemical Properties

References

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