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Azilsartan medoxomil monopotassium

Chemical Structure : Azilsartan medoxomil monopotassium

CAS No.: 863031-24-7

Azilsartan medoxomil monopotassium (TAK-491 monopotassium)

Catalog No.: PC-45274Not For Human Use, Lab Use Only.

Azilsartan medoxomil monopotassium (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.

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Biological Activity

Azilsartan medoxomil monopotassium (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.

Physicochemical Properties

M.Wt 606.6239
Formula C30H23KN4O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, potassium salt (1:1)

References

1. French C, et al. J Cardiovasc Pharmacol. 2011 Aug;58(2):143-8.

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