Chemical Structure : Azvudine
Catalog No.: PC-63018Not For Human Use, Lab Use Only.
Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM.
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Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM; inhibits RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=10-100 nM).
M.Wt | 286.223 | |
Formula | C9H11FN6O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Klumpp K, et al. J Biol Chem. 2008 Jan 25;283(4):2167-75.
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