B0045

Chemical Structure : B0045

Catalog No.: PC-26920Not For Human Use, Lab Use Only.

B0045 is a specific, second-generation inhibitor of DCAF1 (Vpr-binding protein, VprBP), blocks VprBP-mediated H2AT120p and reactivates growth regulatory genes, resulting in a significantly lower proliferative capacity of prostate cancer cells.

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Biological Activity

Physicochemical Properties

M.Wt	380.85
Formula	C19H13ClN4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2-(5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl)hydrazineylidene)methyl)phenol

References

1. Sungmin Kim, et al. Cell Commun Signal. 2026 May 26. doi: 10.1186/s12964-026-02956-3.

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B0045

Biological Activity

Physicochemical Properties

References

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