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BACH2 inhibitor compound 8

Chemical Structure : BACH2 inhibitor compound 8

CAS No.: 1325718-66-8

BACH2 inhibitor compound 8

Catalog No.: PC-72817Not For Human Use, Lab Use Only.

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.
BACH inhibitor compound 8 lowered glycemia and increased plasma insulin levels in diabetic mice, and restored insulin secretion in diabetic mice and human islets.

Physicochemical Properties

M.Wt 465.451
Formula C20H18F3N5O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Methyl-2-(6-trifluoromethoxy-benzothiazol-2-ylamino)-1H-benzoimidazole-5-carboxylic acid (2-methoxy-ethyl)-amide

References

1. Jinsook Son, et al. J Clin Invest. 2021 Dec 15;131(24):e153876.

2. Patent WO2012094580

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