BAY-439 (BAY439)

Chemical Structure : BAY-439

Catalog No.: PC-26792Not For Human Use, Lab Use Only.

BAY-439 is a potent and selective inhibitor of human phospholipase A2 Group V (hPLA2-G5) with biochemical IC50 of 7 nM and KD of 214 nM in the SPR binding assay.

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Biological Activity

BAY-439 is a potent and selective inhibitor of human phospholipase A2 Group V (hPLA2-G5) with biochemical IC50 of 7 nM and KD of 214 nM in the SPR binding assay.

Physicochemical Properties

M.Wt	364.45
Formula	C21H24N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-((2-(ethylamino)pyridin-4-yl)ethynyl)phenoxy)piperidine-1-carboxamide

References

1. Langer G, et al. J Med Chem. 2026 May 19. doi: 10.1021/acs.jmedchem.6c00488.

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BAY-439 (BAY439)

Biological Activity

Physicochemical Properties

References

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