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Chemical Structure : BAY 249716
Catalog No.: PC-49087Not For Human Use, Lab Use Only.
BAY 249716 is a small molecule that modulate mutant p53 condensation, showed significant stabilization of all three p53 protein variants, p53WT p53R175H and p53Y220C.
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BAY 249716 is a small molecule that modulate mutant p53 condensation, showed significant stabilization of all three p53 protein variants, p53WT p53R175H and p53Y220C.
BAY 249716 exhibits anti-proliferative activity in a set of cell lines with different p53 mutation status with low-uM IC50 values.
| M.Wt | 288.753 | |
| Formula | C13H9ClN4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Clara Lemos, et al. iScience. 2020 Sep 25; 23(9): 101517.
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