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BCAT2-IN-2

Chemical Structure : BCAT2-IN-2

CAS No.: 2581243-32-3

BCAT2-IN-2

Catalog No.: PC-26619Not For Human Use, Lab Use Only.

BCAT2-IN-2 is a potent, selective, in-vivo efficacious BCATm (BCAT2) inhibitor with pIC50 of 7.3, 100-fold selective for BCATm over BCATc.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BCAT2-IN-2 is a potent, selective, in-vivo efficacious BCATm (BCAT2) inhibitor with pIC50 of 7.3, 100-fold selective for BCATm over BCATc.

Physicochemical Properties

M.Wt 538.46
Formula C25H24BrN5O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3-(5-bromothiophene-2-carboxamido)cyclohexyl)-N-methyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamide

References

1. Hongfeng Deng, et al. ACS Med Chem Lett. 2016 Feb 8;7(4):379-84.

2. Li JT, et al. Nat Cell Biol. 2020 Feb;22(2):167-174.

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